Intracytoplasmic Morphologically Selected Sperm Injection (IMSI)

What is IMSI?

Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) is an advanced form of ICSI (Intracytoplasmic Sperm Injection) that uses a high-powered microscope to magnify sperm by up to 6,000 times. This allows embryologists to select the most morphologically perfect sperm for injection into the egg. 

By examining the sperm’s structure in detail, IMSI significantly improves the chances of fertilization and the quality of embryos, especially for cases of severe male infertility.

The procedure provides an enhanced focus on sperm selection, reducing risks of chromosomal abnormalities, and increasing the likelihood of a healthy pregnancy.

Who Can Benefit from IMSI?

IMSI treatment at Mamata Fertility Hospital is beneficial for couples dealing with specific fertility challenges, particularly related to male factor infertility. Below are key scenarios where IMSI can make a difference:

1. Severe Male Factor Infertility

IMSI is ideal for men with:

• High levels of abnormal sperm morphology (teratozoospermia).
• Poor sperm motility (asthenozoospermia).
• A history of failed fertilization in previous IVF or ICSI attempts.

2. Repeated IVF or ICSI Failures

Couples who have undergone multiple unsuccessful fertility treatment cycles, especially with poor-quality embryos, should consider IMSI.

3. Advanced Age and Genetic Concerns

IMSI reduces the risks of chromosomal abnormalities, making it especially valuable for older couples or those seeking reassurance about genetic health.

4. Low Sperm Count or Motility

For men with severely low sperm count (oligospermia) or poor sperm motility, IMSI enhances the chances of selecting healthy sperm capable of achieving successful fertilization.

5. Couples with Recurrent Pregnancy Loss

Choosing morphologically perfect sperm can play a significant role in reducing chromosomal defects, providing hope for couples who have faced recurrent miscarriages.

The IMSI Procedure

The IMSI procedure is meticulous and requires advanced laboratory technology along with the expertise of highly trained embryologists. Here’s how the process works:

1. Fertility Assessment

The process begins with comprehensive testing and consultations to assess both partners’ reproductive health and identify potential concerns.

2. Ovarian Stimulation and Egg Retrieval

The woman undergoes ovarian stimulation to produce multiple eggs, which are then retrieved using ultrasound-guided aspiration under sedation.

3. Sperm Selection with High Magnification

Semen is collected from the male partner or a donor. Using an ultra-high-powered microscope (over 6,000x magnification), embryologists examine sperm health at a detailed level to select the best sperm with normal structure and minimal abnormalities.

4. Sperm Injection

The selected sperm is carefully injected into the cytoplasm of healthy, mature eggs. This step requires precision and expertise to ensure successful fertilization.

5. Embryo Cultivation and Transfer

Fertilized eggs are cultured in the lab for several days, and the most viable embryos are transferred into the woman’s uterus.

6. Pregnancy Test

Two weeks after the embryo transfer, pregnancy is confirmed via blood tests.

Success Rates of IMSI

The success of IMSI treatment in Secunderabad depends on factors such as the couple’s age, the quality of eggs and sperm, and their overall health condition.

General Success Rates

• Improved Fertilization: IMSI enhances fertilization outcomes by selecting top-quality sperm.
• Higher Pregnancy Rates: Pregnancy rates can increase by 10–20% compared to traditional ICSI, particularly for cases of severe male infertility.
• Healthier Embryos: Better sperm selection results in more viable embryos with reduced chromosomal abnormalities.

At Mamata Fertility Hospital, our state-of-the-art IMSI facilities and experienced team improve your chances of achieving a successful pregnancy.

Risks and Considerations

While IMSI is highly effective, it is essential to understand the risks, which are rare and manageable with expert care.

1. Egg Damage – Minimal risk of egg damage during sperm injection.
2. Multiple Pregnancies – Transferring more than one embryo may lead to twins or triplets.
3. Ovarian Stimulation Risks – Risks such as Ovarian Hyperstimulation Syndrome (OHSS) from fertility medications are closely monitored.

At Mamata Fertility Hospital, we discuss all risks in detail before treatment and ensure measures are in place for a safe and successful procedure.

Cost of IMSI in Secunderabad

The cost of IMSI treatment at Mamata Fertility Hospital is competitive, ensuring advanced services remain accessible to all couples.

Estimated Costs

• Initial Evaluation & Tests: ₹10,000–₹20,000
• IMSI Procedure (Including IVF): ₹2.2–₹3.5 lakhs per cycle
• Additional Costs: Embryo freezing, PGT, or surgical sperm retrieval if needed

We also offer flexible payment options and counseling to help you plan your fertility treatment effectively.

IUI vs IVF vs ICSI vs IMSI

Understanding the differences between these fertility treatments is crucial when deciding your best course of action.

IUI (Intrauterine Insemination)

• Procedure: Sperm is placed in the uterus during ovulation for natural fertilization.
• Benefits: Non-invasive, affordable.
• Ideal For: Mild infertility cases.

IVF (In Vitro Fertilisation)

• Procedure: Eggs and sperm are combined in a lab, and embryos are transferred into the uterus.
• Benefits: Higher success rates, allows genetic testing.
• Ideal For: Moderate infertility, tubal issues, repeated IUI failures.

ICSI (Intracytoplasmic Sperm Injection)

• Procedure: A single sperm is directly injected into an egg.
• Benefits: Addresses male infertility issues like low motility.
• Ideal For: Severe male infertility, failed IVF attempts.

IMSI (Intracytoplasmic Morphologically Selected Sperm Injection)

• Procedure: Uses high magnification to select top-quality sperm, which is injected into eggs.
• Benefits: Improved fertilization and embryo quality, reduces chromosomal defects.
• Ideal For: Severe male infertility, recurrent IVF failures, genetic concerns.

Making the Right Decision for Your Case

At Mamata Fertility Hospital, we understand that every couple’s circumstances are unique. Choosing between IUI, IVF, ICSI, or IMSI involves evaluating various factors.

Key Considerations

1. Age and Health of Both Partners
• Younger couples may find IUI effective, while older couples are better suited for IVF, ICSI, or IMSI.
2. Fertility Challenges
• Mild issues can be addressed with IUI or IVF. Severe male infertility calls for ICSI or IMSI.
3. Previous Treatment Results
• Multiple failed cycles of IUI or IVF point to the necessity of considering advanced treatments like IMSI.
4. Financial Considerations
• IUI is cost-effective, while IVF, ICSI, and IMSI offer higher success rates in complex cases.
5. Genetic Concerns
• IMSI reduces risks of chromosomal abnormalities, making it an excellent choice for older couples or those with recurrent pregnancy loss.

Why Choose Mamata Fertility Hospital?

Our specialists evaluate every aspect of your health, lifestyle, and fertility goals to recommend the most suitable option. We prioritize transparency, education, and personalized care to ensure your decision feels right.

Contact us today to schedule your consultation and explore the best solutions for your fertility challenges. Together, we’ll help you start your family with confidence!

FAQs

1. How is IMSI different from ICSI?

While ICSI involves injecting a single sperm directly into the egg, IMSI takes it further by using high magnification for more precise sperm selection.

2. Is IMSI more effective than IVF or ICSI?

IMSI offers improved fertilization and higher-quality embryos, making it ideal for certain cases of severe male infertility where IVF or ICSI alone may not be sufficient.

3. Is IMSI safe?

Yes, IMSI is a safe and well-established procedure. Risks are rare and managed by our expert team.

4. How many cycles of IMSI are usually needed?

The number of cycles varies depending on individual health conditions, but IMSI often improves outcomes within fewer cycles.

5. Does IMSI work for older couples?

Yes, IMSI is particularly beneficial for older couples and those concerned about reducing genetic risks.

WHAT PATIENTS EXPERIENCE AT MAMATA FERTILITY?

“I had an excellent first visit to Mamata Hospitals, where I met Dr. Mamata madam and Dr. Arti. Madam and Dr cheatn The process was systematic, instilling confidence that my issues will be effectively addressed. The staff and doctors were incredibly friendly and supportive, making me feel at ease. Their professionalism and warmth have given me great confidence in their care. I look forward to sharing more about my journey in detail.”

Vishu S.N

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At Mamata Fertility Hospital in Secunderabad, advanced treatments like IMSI provide hope for couples facing complex fertility challenges. We’re here to guide and support you every step of the way.

Book your consultation today and take the first step toward achieving your parenthood dreams with IMSI treatment in Secunderabad.